Almost everybody knows how painful and uncomfortable toothache feels. A general term “toothache” means pain caused by various acute and chronic inflammatory-degenerative diseases of the maxillofacial area (cavities, pulpitis, periodontitis) and pain after performing various dental procedures in the maxillofacial area (tooth extraction, root canal filling). Let’s consider advantages of non-steroid anti-inflammatory drugs (NSAIDs) for toothache or any kind of pain caused by teeth
It is recommended to see a dentist immediately if you have a toothache or pain in a dental area. The longer you wait, the worse it can get. The consequences of postponed visit to a dentist can be very severe. If you experience toothache it is necessary to see a doctor right away. Don’t listen to your fears because it can cost you dearly. Remember that taking painkillers will only temporarily reduce toothache, but it cannot replace treatment. The problem will remain until you see a doctor.
According the international classification Celebrex belongs to selective Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). Celebrex selectively blocks the enzyme called cyclooxygenase-2 (COX-2). It means that Celebrex has anti-inflammatory, analgesic and antipyretic action.
According to clinical studies patients with dental pain after tooth extraction felt pain relief after 28 minutes after taking 400 mg of Celebrex. Its quick effect as a painkiller is compared to injectable forms of other NSAIDs. It makes Celebrex a good alternative to parenteral administration of NSAIDs. A significant advantage of Celebrex is its prolonged pain relieving action that lasts for 12 hours.
This is the only NSAID prescribed to patients with a peptic disorders in combination with gastroprotectants. Celebrex is a safe way to treat patients with arterial hypertension and heart failure. It can be combined with aspirin that makes it safe for patients with high cardiovascular risk.
The efficacy of Celebrex as an emergency painkiller is confirmed by the study conducted by Dr. S. Derry and his co-authors. They examined the results of 8 randomized clinical trials (a total of 1380 patients) to come to the conclusion. A single administration of 200 or 400 mg of celecoxib (the main component of the Celebrex ) provided a significant relief of intense and acute postoperative pain.
According clinical recommendations, Celecoxib should be used in a single dose of 400 mg for acute pain. A lower dosage (200 mg) can be used to maintain the analgesic effect or to provide a long-term treatment of moderately pronounced chronic pain.
It is recommended to use Celecoxib for preventive pain relief and take it 1-2 hours before the dental surgical procedure like, for example, tooth extraction.
Compared to other nonselective NSAIDs, Celebrex reduced risk of postoperative bleeding because it has a coagulant action.
Clinical studies proved that patients on Celebrex had less bleeding from the area of surgical wound during and after the surgery compared to the patients receiving nonselective NSAIDs. The high efficacy and safety of Celebrex was proven by Dr. Nikanne’s study evaluating the patients undergoing tonsillectomy.
The excessive post-surgery bleeding was observed only in one patient on Celecoxib compared to 6 patients on Ketoprofen for pain relief. In outpatient dental practice, Celebrex is used not only in the complex therapy of inflammatory processes and pain in the maxillofacial area, but also for pre-anesthetic treatment as part of the medical preparation for dental surgical procedures. It is also recommended to reduce postoperative craniofacial pain and severe toothache, edema and inflammation.