Contraindications for celecoxib

Do not take Celebrex (Celecoxib) if:
  • your doctor has told you that you have a serious heart or blood vessel disease that affects the circulation in the brain or limbs
  • have severe liver problems
  • your doctor will decide if your condition is too severe to take this medicine.
  • you have problems with your kidney function
  • you are undergoing coronary bypass surgery (CABG)
  • you have had an asthma attack, hives, itching, rash or a runny nose after taking aspirin or non-steroidal anti-inflammatory drugs (NSAIDs, medicines used to treat pain and inflammation), including other medicines Coxib
  • many medications used to treat headache, pain in the period and other aches and pains contain aspirin or an NSAID.
  • if you are allergic to aspirin, NSAIDs, or other Coxib medications and taking Celebrex, these symptoms can be serious.
  • you have an allergy to Celecoxib. Symptoms of an allergic reaction to these medicines may include:
    • asthma, wheezing or shortness of breath
    • swelling of the face, lips, or tongue that may cause difficulty swallowing or breathing
    • urticaria, itching or rash
    • fainting.
  • if you are allergic to sulphonamides or any of the ingredients in the capsule and taking Celebrex, these symptoms can be serious. Ask your doctor or pharmacist if any of this applies to you.
  • you are already taking an NSAID
  • you have gastric ulcer or bleeding
  • you have Irritable Bowel Disease
  • you have heart failure
  • the expiration date printed on the packaging has passed, although the capsules may look good
  • if you take this medicine after the expiration date has passed, it may not work as well.
  • the container is torn or shows signs of alteration.
You should tell your doctor if:
  • you currently have diabetes, high blood pressure, high cholesterol, heart failure, or have a history of heart problems or strokes or problems with circulation in your extremities
  • you have any allergies to:
    – any other medicine
    – any other substance, such as food, dyes or preservatives
  • you are pregnant or intend to become pregnant. NSAIDs, which are related medications, have been associated with reversible infertility in some women. Use of NSAIDs in early pregnancy may increase the risk of miscarriage. There is no information on the use of Celebrex during pregnancy. Celebrex can affect your developing baby if it is taken within the last 3 months of pregnancy. Celebrex is not recommended during pregnancy, unless your doctor considers it essential.
  • ¬†you are breastfeeding or intends to breastfeed.Small amounts of celecoxib pass into breast milk, so taking Celebrex during breast-feeding should be discussed with your doctor.
  • you have other health problems including:
    • liver or kidney problems
    • asthma, hives, itching, rash, or runny nose
    • high blood pressure or fluid retention
    • peptic ulcer (ie, stomach or duodenal ulcer), a recent history of one, or have had peptic ulcers before
    • vomiting of blood or material that looks like coffee beans
    • hemorrhage of the rectum (posterior passage), have black sticky bowel movements (feces) or bloody diarrhea.
  • you are taking Celebrex along with any medication used to treat high blood pressure and other heart problems such as ACE inhibitors, angiotensin receptor antagonists, beta-blockers, and diuretics. When taken together these medications can cause kidney problems.
  • you drink large amounts of alcohol
  • you are a smoker
  • you currently have an infection. If you are given Celebrex while you have an infection, you can hide some of the signs of an infection.
Some medications and Celebrex (Celecoxib) may interfere with each other. These include:
  • any medication used to treat high blood pressure and other heart problems such as ACE inhibitors, angiotensin receptor antagonists, beta blockers, or diuretics (also called liquid or water tablets)
  • fluconazole, an antifungal agent
  • lithium, a medicine used to treat some types of depression
  • warfarin or similar medicines like Eliquis (apixaban), Xarelto (rivaroxaban) or Pradaxa (dabigatran), medicines used to stop blood clots
  • aspirin or salicylates, medicines used to treat pain
  • antacids, medicines used to treat indigestion
  • some medicines used to treat diabetes
  • methotrexate, a drug used to treat arthritis and some cancers
  • ciclosporin, a drug used to suppress the immune system
  • certain medications used to treat pain and inflammation called non-steroidal anti-inflammatory drugs (NSAIDs) or (corticosteroid) steroids.
Your doctor may need to adjust your dosage or give you additional advice if you are also taking Celebrex (Celecoxib).